New applications of nmr in drug discovery and development

New applications of nmr in drug discovery and development By
2013 | 584 Pages | ISBN: 1849734445 | PDF | 17 MB
Content: Introduction; Part I. Small Molecules, Proteins, Cellular Systems: New Applications of High; Resolution NMR in Drug Discovery and Development; Solid-state NMR in Drug Discovery and Development; Part II. The Whole Organism in Vivo: Increased Sensitivity Using Cryogenic; Radiofrequency Coils: Application to In Vivo Phenotyping of Mice; Recent Developments of Contrast Agents, CEST and Low Fields; Pharmacological fMRI in Drug Discovery and Development; Part III. Translational drug discovery: From Biological Models to the Clinics; Translational Magnetic Resonance Imaging and Spectroscopy: Opportunities and Challenges