English | 2020 | ISBN: 9780750320641 | 235 pages | True (PDF,EPUB,MOB) | 100.16 MB
This
book provides a thorough introduction to the topic of mathematical modeling of
electrical activity in the heart, from molecular details of ionic channel
dynamics to clinically derived patient-specific models. It discusses how
cellular ionic models are formulated, introduces commonly used models and
explains why there are so many different models available. The chapters cover
modeling of the intracellular calcium handling that underlies cellular
contraction as well as modeling molecular-level details of cardiac ion channels,
and specialized topics such as cardiomyocyte energetics and
signalling pathways. It is an excellent resource for experienced and
specialized researchers in the field, but also biological scientists with a
limited background in mathematical modelling and computational methods.
Key Features
Thorough introduction to the topic of mathematical modeling of electrical activity in the heart
Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations
In addition to being experts in the field, the contributing authors are expert science communicators
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