English | 2022 | ISBN: 3527346899 | 365 pages | True PDF | 22.38 MB
Learn to master a powerful technology to enable a faster drug discovery workflow
The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors-with integrated analysis of the resulting products-provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort.
In Flow and Microreactor Technology in Medicinal Chemistry , early adopters of this ground-breaking technology describe its current and potential uses in medicinal chemistry. Based on successful examples of the use of flow and microreactor synthesis for drug-like compounds, the book introduces current as well as emerging uses for automated synthesis in a drug discovery context.
Flow and Microreactor Technology in Medicinal Chemistry readers will also find:
Numerous case studies that address the most common applications of this technology in the day-to-day work of medicinal chemistsHow to integrate flow synthesis with drug discoveryHow to perform enantioselective reactions under continuous flow conditions
Flow and Microreactor Technology in Medicinal Chemistry is a valuable practical reference for medicinal chemists, organic chemists, and natural products chemists, whether they are working in academia or in the pharmaceutical industry.
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